Although SNP genotypes are inherited from the family, the combination presented in each individual may not necessarily exhibit familial traits. However, since family members living together are often exposed to the same environmental factors, it is recommended that family members also assess their disease risks and participate in health management together.

Children can undergo the test and learn about their 'relative risk' genotype. However, since the current disease databases mostly cover data accumulated over no more than 20 years, primarily from adults over 40, there is more statistical significance for that age group. Diseases typically have a progression before they manifest, and they are usually recorded in adulthood. Therefore, the test results for individuals of a certain age are more empirically validated. If children undergo the test, the report will estimate their risk for the 40–49 age range.

Although newborns can also undergo genetic testing, oral sampling is challenging, and they have not yet been exposed to long-term environmental factors, so it is generally not recommended.

As long as a successful oral sample can be obtained, the test can be conducted. However, certain medications or treatments may reduce the number of mucosal cells in the oral cavity, potentially affecting the quality of extracted DNA, which will need to be verified by the lab. Additionally, this test assesses an individual's genetic predisposition to disease risk and is not intended for diagnostic purposes, so it does not reflect current medical conditions."

Each SNP genotype only needs to be identified once in a lifetime, as it does not change easily.

Please follow the sampling instructions provided inside the box. There is also a QR code in the box that links to a video guide, which will help you understand the process more clearly. The questionnaire and consent form included are important documents and contain information needed for the analysis, so please fill them out carefully. After sampling, simply send back the sample along with the completed questionnaire and consent form, and you will receive a full report from Phalanx within 2–4 weeks.

The collection tube contains a stabilizer that ensures the sample quality remains intact at room temperature for over two weeks, so refrigeration is not necessary. However, please avoid direct sunlight. For safety reasons, it is recommended to send the sample back as soon as possible after collection.

Phalanx has designed the questionnaire to be as effortless as possible for users, so only the questions with the highest relevance and contribution to disease risk are included. We aim for simplicity while maintaining strong predictive power and empirical support.

Keloid is a condition where thickened scars form on the skin as a result of injury or surgery during the healing process. It mainly occurs in individuals with a genetic predisposition, where abnormal overgrowth of fibroblasts happens during wound healing. Keloids can affect people of all ages, but they are more common in Asians and Black individuals aged 10 to 30. Generally, not every wound will result in a keloid, but deeper wounds or those located in areas of higher skin tension (such as the chest or arms) have a higher chance of developing keloids. Once a keloid forms, it is difficult to remove through surgery, as the procedure may create a larger wound, leading to another keloid. The best way to prevent keloids is to avoid wound formation. Individuals with a higher genetic risk of keloids or a history of keloids should avoid cosmetic surgery, tattoos, or ear piercings.

Compared to other cancers, research on SNPs related to oral cancer is currently less active, and the studies published are on a smaller scale. The credibility of SNP risk data for oral cancer in the literature is not very high. To ensure prediction accuracy, it has been temporarily excluded. Once larger-scale SNP studies on oral cancer are available, Phalanx will include oral cancer in our personalized genomic services for cancer risk.

Since parents each pass down half of their DNA to their child, the child's genetic makeup will be similar to both parents. Additionally, children typically live with their parents, so they are exposed to similar environmental factors (such as dietary habits), which can lead to some similar test results. However, this is not absolute, and genetic testing is still necessary to confirm these similarities.

The occurrence rate in the report primarily predicts the likelihood of developing a disease in the future. The predicted age range varies depending on the actual age of the client at the time of testing. The prediction principles are as follows:

• When you are ≤45 years old, the prediction is for disease occurrence between ages 40-49.
• When you are between 45-55 years old (including 55), the prediction is for disease occurrence between ages 50-59.
• When you are between 55-65 years old (including 65), the prediction is for disease occurrence between ages 60-69.
• When you are >65 years old, the prediction is for disease occurrence at age 70 and above.

Since the occurrence rate of chronic diseases is generally lower before age 40, predictions are not made for that age group.

The disease occurrence rate for the population varies not only by age group but also by gender. Since you are male, your report provides the occurrence rate for 'men' in the 40-49 age group, whereas your wife, being female, is provided with the occurrence rate for 'women' in the 40-49 age group. This is why the values differ between the two reports for the same age group.

In the report, each genetic locus is colored based on how many risk alleles are present: for example, having two risk alleles is shown in red, one risk allele in yellow, and zero risk alleles in no color. Each SNP's genotype has a corresponding relative risk index weight, and the final risk score is calculated based on these weights. Therefore, even if many markers are shown in red, it doesn't necessarily mean the overall risk is high.

Brain tumors can be classified into benign and malignant types. The glioma risk assessed in our test refers specifically to malignant brain tumors, and different types of brain tumors have different genetic and environmental factors involved. Your low risk for glioma does not mean that you are completely immune to developing glioma or other types of brain tumors. If you have been diagnosed with glioma, it could be due to factors not covered by our assessment, such as viral infections, occupational exposures (e.g., handling chemicals, working at a gas station), or head injuries. It's advisable to discuss these possibilities with your consultant or physician.